Identification by Differential Display of Transcripts Regulated during Hematopoietic Differentiation
نویسندگان
چکیده
منابع مشابه
Identification of transcripts overexpressed during airway epithelium differentiation.
Human airway epithelium, the defence at the forefront of protecting the respiratory tract, evacuates inhaled particles by a permanent beating of epithelial cell cilia. When deficient, this organelle causes primary ciliary dyskinesia, and, despite numerous studies, data regarding ciliated cell gene expression remain incomplete. The aim of the present study was to identify genes specifically expr...
متن کاملIdentification by mRNA differential display of two up-regulated genes as candidate mediators of AIDS dementia.
BACKGROUND In the dementia associated with acquired immunodeficiency syndrome (AIDS), indirect pathomechanisms are important mediators of progressive neuronal injury and variable candidate molecules of potential pathogenetic importance have been identified. MATERIALS AND METHODS In an attempt to characterize additional mediators of human immunodeficiency virus type 1 (HIV-1)-induced neurotoxi...
متن کاملIdentification of glucocorticoid- and adenovirus E1A-regulated genes in lung epithelial cells by differential display.
Adenovirus infection has been implicated in the pathogenesis of lung inflammatory diseases for which glucocorticoids provide effective antiinflammatory treatment. In this study, the differential display assay was used to identify messenger RNAs (mRNAs) differentially expressed in dexamethasone (1 microM for 24 h)-treated A549 lung epithelial cells compared to A549 cells transfected with the ade...
متن کاملIdentification of MEF2-regulated genes during muscle differentiation.
Although a great deal has been elucidated concerning the mechanisms regulating muscle differentiation, little is known about transcription factor-specific gene regulation. Our understanding of the genetic mechanisms regulating cell differentiation is quite limited. Much of what has been defined centers on regulatory signaling cascades and transcription factors. Surprisingly few studies have inv...
متن کاملIdentification by differential display of annexin-VI, a gene differentially expressed during melanoma progression.
To identify genes involved in the melanocyte to malignant melanoma conversion, we have applied differential display to the comparison of syngeneic murine B16F10 (metastatic melanoma) and Melan-a-immortalized melanocyte cell lines. Approximately 7000 bands were analyzed, revealing approximately 80 to be differentially displayed. Reverse Northern blotting and subsequent Northern blotting confirme...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Stem Cells
سال: 1998
ISSN: 1066-5099,1549-4918
DOI: 10.1002/stem.160136